Gastrointestinal Cancer Clinical Trials & Research at Providence Medical Group

Gastrointestinal (GI) cancers encompass a group of malignancies affecting the digestive system, including the esophagus, stomach, liver, pancreas, gallbladder, and intestines. These cancers are among the most prevalent and deadly worldwide, often diagnosed at advanced stages due to the lack of early symptoms. As such, there is a critical need for innovative treatments to improve patient outcomes.

Clinical trials play a vital role in the advancement of GI cancer therapies. These studies are designed to evaluate the safety and efficacy of new treatments, which may include chemotherapy, targeted therapies, immunotherapies, and surgical techniques. By conducting rigorous trials, researchers can identify better ways to treat, manage, and potentially cure GI cancers.

Providence Medical Group is currently enrolling patients for the following Gastrointestinal studies:


A Study of Repotrectinib (TPX-0005) in Patients With Advanced Solid Tumors Harboring ALK, ROS1, or NTRK1-3 Rearrangements (TRIDENT-1)​

Treatment agent: Repotrectinib (TPX-0005) oral medication
Physician: Ian Anderson, MD
Study Coordinator: Tracy Foster // tracy.foster@stjoe.org // 707-521-3830
Study Resources: https://www.clinicaltrials.gov/study/NCT03093116
Sponsor: Turning Point Therapeutics, Inc.
Location: Providence Cancer Center, Santa Rosa, CA


A Phase II, Open-label, Multi-centre Study to Evaluate Safety, Tolerability, Efficacy, PK, and Immunogenicity of AZD0901 as Monotherapy and in Combination with Anti-cancer Agents in Participants with Advanced Solid Tumours Expressing Claudin 18.2 (CLARITY-PanTumour01)

Treatment agent: AZD0901 is a novel antibody-drug conjugate (ADC) targeting Claudin (CLDN) 18.2.
Physician: Ian Anderson, MD
Study Coordinator: Teresa Lund // teresa.lund@stjoe.org // 707-521-3830
Study Resources: Study Details | AZD0901 in Participants With Advanced Solid Tumours Expressing Claudin18.2 | ClinicalTrials.gov
Sponsor: AstraZeneca
Location: Providence Cancer Center, Santa Rosa, CA


A Phase 1b/2, Multicenter, OpenLabel Study of Anti-CEACAM5 Antibody-Drug Conjugate M9140 in Participants With Advanced Solid Tumors (EMD Serono MS202329-0010 PROCEADE)

Treatment agent: Anti-CEACAM5 Antibody-Drug Conjugate M9140

Physician: Ian Anderson, MD
Study Coordinator: Camille Shaffer // camille.shaffer@stjoe.org // 707-521-3830
Study Resources: Study Details | Study of Anti-CEACAM5 ADC M9140 in Participants With Advanced Solid Tumors (PROCEADE PanTumor) | ClinicalTrials.gov
Sponsor: EMD Serono Research & Development Institute, Inc
Location: Providence Cancer Center, Santa Rosa, CA


Amivantamab + Chemotherapy Versus Cetuximab + Chemotherapy in Treatment-naïve Participants with KRAS/NRAS and BRAF Wild-type Colorectal Cancer (OrigAMI-2)

Treatment agent: JNJ-61186372 (amivantamab)
Physician: Yao Yao Pollock, MD
Study Coordinator: Melissa Ulrich // melissa.ulrich@providence.org // 707-521-3830
Study Resources: Study Details | A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer | ClinicalTrials.gov
Sponsor: Janssen Research & Development, LLC
Location: Providence Cancer Center, Santa Rosa, CA


Amivantamab + FOLFIRI Versus Cetuximab/Bevacizumab + FOLFIRI in Participants With Recurrent KRAS/NRAS and BRAF Wild-type Colorectal Cancer (OrigAMI-3)

Treatment agent: JNJ-61186372 (amivantamab)
Physician: Yao Yao Pollock, MD
Study Coordinator: Melissa Ulrich // melissa.ulrich@providence.org // 707-521-3830
Study Resources: Study Details | A Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in Participants With KRAS/NRAS and BRAF Wild-type Colorectal Cancer Who Have Previously Received Chemotherapy | ClinicalTrials.gov
Sponsor: Janssen Research & Development, LLC
Location: Providence Cancer Center, Santa Rosa, CA


A Phase 1/1b Study of AB598 Monotherapy and Combination Therapy in Participants with Advanced Malignancies

Treatment agent: AB598 targets human CD39
Physician: Ian Anderson, MD
Study Coordinator: Teresa Lund // teresa.lund@stjoe.org // 707-521-3830
Study Resources: Study Details | Study of AB598 Monotherapy and Combination Therapy in Participants With Advanced Cancers | ClinicalTrials.gov
Sponsor: Arcus Biosciences, Inc
Location: Providence Cancer Center, Santa Rosa, CA

Sonoma and Napa Providers

Our Sonoma and Napa Provider

Brian Lockwood Hanson, MD
Brian Lockwood Hanson, MD
Gastroenterology
City:  Santa Rosa
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